STRETCH

Skeletal Research Enhancing Training Collaboration & Health

Skeletal Research Enhancing Training Collaboration & Health (STRETCH)

STRETCH builds on the robust infrastructure of the NIAMS P30-supported UCSF Core Center in Musculoskeletal Biology and Medicine (CCMBM) and the University of California (UC) Leadership Excellence through Advanced Degrees (LEADS) program.

This program stimulates collaboration among scientists by supporting students throughout a two-year research experience that incorporates two academic years and one summer of research at the home campus, and a second summer of research at another UC. STRETCH Scholars will be paired with a faculty mentor from any of the following UC campuses:

UC Berkeley
UC Davis
UC Irvine
UC Los Angeles
UC Merced

UC Riverside
UC Santa Barbara
UC Santa Cruz
UC San Diego
UC San Francisco

Apply to become a STRETCH Scholar

Select this student application to be considered as a STRETCH scholar.

Preview scholar application questions (click to expand)

Apply to become a STRETCH Faculty Mentor

Select this application to be considered as a STRETCH faculty mentor.

Preview mentor application questions (click to expand)

If you have questions regarding the application process, please contact Pui Yee Law.

FAQs (click to expand)

Q. Who qualifies to apply to become a STRETCH Scholar?
A. Students who are part of UC LEADS may apply to become a STRETCH Scholar.

Q. How much is the stipend for this program?
A. Each STRETCH Scholar will receive a stipend at the beginning of the academic year for their two-year research experience ($12,000 total).

Q. Is there any funding for research expenses?
A. Each research project will receive $8,000 credit for musculoskeletal core services at CCMBM.

Q. When will participants be selected?
A. Participants will be selected after your home campus UC LEADS application review process. Mentors will be selected during February 2023.

Q. Who are the UC STRETCH contacts at each campus?
A. There are currently nine faculty mentors participating in the program:
Grace O'Connell
Campus: UC Berkeley
Research: soft tissue mechanobiology, specifically studying how the mechanical behavior of fiber reinforced tissues from the musculoskeletal system is changed with age and disease.
Research Focus: Tissue Engineering

Clare Yellowley-Genetos

Campus: UC Davis

Research: regulatory role of the bone microenvironment on both cell fate and function; in particular the influence of the mechanical environment and environmental oxygen availability on skeletal cells.

Research Focus: Molecular & Cell

Gabriela Loots

Campus: UC Davis/LLNL

Research: Animal models and cell-based tissue mimetric approaches to answer key questions in bone, cartilage, and caner. Developing treatments for osteoporosis, osteoarthritis traumatic bone injury, and preventing bone metastasis.

Research Focus: Molecular & Cell, Genomics

Olaronke Olabisi

Campus: UC Irvine

Research: biosynthetic materials, which combine synthetic and biological materials and can control cell and tissue function. Develop wound dressings that accelerate the healing of chronic diabetic wounds faster than normoglycemic wounds and combination seashell-synthetic biomaterials capable of directing bone formation in microscopic patterns.

Research Focus: Tissue Engineering

Karen Lyons

Campus: UC Los Angeles

Research: investigate the functions of secreted factors in skeletal development and postnatal maintenance. Elucidation of the functions and mechanisms of BMP and TGF-beta signaling pathways in cartilage and bone.

Research Focus: Molecular & Cell, Developmental

Jennifer Manilay

Campus: UC Merced

Research: influence of communication between bone and hematopoietic stem cells on immune cell fate decisions. Studies questions at the crossroads of developmental biology, stem cell bilogy and immunology.

Research Focus: Developmental Immunology

Nicole I. zur Neiden

Campus: UC Riverside

Research: utilizes pluripotent stem cell models as well as mouse and zebrafish models to study developmental bone formation (osteogenesis). Developed murine embryonic stem cell protocols for chondrogenic and osteogenic differentiation into matrix-secreting chondrocytes and mineralized osteoblasts respectively. Study normal and abnormal osteogenesis, including the molecular mechanisms that drive osteogenic fate or interfere with it.

Research Focus: Molecular & Cell

Kimberly Cooper

Campus: UC San Diego

Research: Evolution of developmental mechanisms that diversified the vertebrate limb musculoskeletal system. Genetic mechanisms that establish and vary skeletal proportion by controlling growth plate cartilage elongation rate and duration.

Research Focus: Developmental

Tamara Alliston

Campus: UC San Francisco

Research: crosstalk between biochemical and physical cues in the skeleton, identifying mechanisms by which they direct skeletal cell behavior and specify the material and mechanical properties of bone and cartilage in health, aging, and disease.

Research Focus: Molecular & Cell, Mechanobiology

Welcome the 2023 STRETCH Mentors & Scholars!

Earlier this month, the inaugural cohort of STRETCH mentors and scholars met with CCMBM staff and UC LEADS representatives to officially launch their research projects. Scholars and mentors represent a network of MSK research spanning 6 of the UC campuses: Berkeley, Davis, Los Angeles, Merced, Riverside, San Francisco.

The STRETCH program stimulates collaboration among scientists by supporting students throughout a two-year research experience that incorporates two academic years and one summer of research at the home campus, and a second summer of research at another UC.

TEAM 1: Fibroadipogenic Progenitors as Mediators of Muscle Fibrosis

Sonali Feeley