Current Research
Pilot/Feasibility Projects
Department of Medicine
Identifying Therapies for Fibrous Dysplasia of the Bone Using a Drug Repositioning Strategy
Tools & Technology Projects
Department of Radiology & Biomedical Imaging
Ultra-short Echo Time MRI for Aiding in the Detection of Vessels in Cortical Bone Pore Space
Past CCMBM Projects
Pilot/Feasibility Projects
2022-2023
Department of Medicine
Bone marrow fat and skeletal health in type 2 diabetes
Department of Orthopaedic Surgery
Cellular heterogeneity and sex based differences in human ACL injuries
2021-2022
Department of Orthopaedic Surgery
Nociplastic spinal cord-muscle loop in degenerative disc disease (DDD)
Department of Orofacial Sciences
Role of p75NTR in Osteogenic Differentiation and Skeletal Development using Mouse Model
Department of Physical Therapy & Rehabilitation Science
The Relationship between Gait Biomechanics and Exercise Induced Pain Flares in Patellofemoral Joint Osteoarthritis
2020-2021
Department of Medicine
Advanced ultrasound techniques for the evaluation of total knee arthroplasty
Department of Radiology and Biomedical Imaging
Multi-Task Deep Learning to Develop Automatic Scrapular Shape Extraction from Clinical MR
Department of Orthopaedic Surgery
Multi-Task Deep Learning to Develop Automatic Scrapular Shape Extraction from Clinical MR
2019-2020
Department of Orthopaedic Surgery
The mechanistic pathophysiology associated with paraspinal muscular degeneration and chronic low back pain
2018-2019
Department of Opthamalogy
Mechanistic and Therapeutic Examination of Congenital Skeletal Defects in Col4a1 Mutant Mice
Department of Orthopaedic Surgery
Advanced ultrasound techniques for the evaluation of total knee arthroplasty
2017-2018
Edward Hsiao, MD, PhD
Department of Medicine
Linking Innate Immune Dysfunction to Abnormal Bone Formation
2016-2017
Department of Orthopaedic Surgery
Co-Investigator: Jason Pomerantz, MD
Evaluation of satellite cell function and transplantation in rotator cuff injury
2015-2017
Department of Medicine
Co-Investigator: Farzana Perwad, MD
Central Regulation of Ion transport and Skeletal Mineralization by FGF23 and Klotho
Sergey Magnitsky, PhD
Department of Radiology & Biomedical Imaging
Preclinical MR imaging and spectroscopy of bacteria infection in spinal disc
2015-2016
Department of Opthamalogy
Characterizing skeletal defects in Col4a1 mutant mice
2014-2015
Xiaojuan Li, PhD
Departments of Radiology & Biomedical Imaging, Orthopaeic Surgey
Collaborator: Benjamin Ma, MD
In search of preventive measures for post-traumatic osteoarthritis: Synovial fluid characterization after anterior cruciate ligament injuries using novel techniques and approaches
Department of Orthopaedic Surgery
Endplate dysfunction in disc degeneration: investigating solute transport kinetics, disc cell viability, and new imaging methods
Department of Orthopaedic Surgery
Neuro-regulation of osteoporosis and heterotopic ossification after spinal cord injury
Tools and Technology Projects
2022-2023
Department of Orthopaedic Surgery
Biochemical mechanisms affecting T1ρ relaxation times in the intervertebral disc
2021-2022
Department of Radiology
Establishing Time-Lapse HR-pQCT technique for Determining Total Bone Turnover in Patients with CKD
Liping Wang, MD, PhD
Department of Medicine
Spatial Profiling WNT Signaling Pathway in PTH-treated Mouse Bones
2020-2021
Department of Orofacial Sciences
Elucidating the epigenetic regulation of p75NTR in skeletal development
Department of Radiology & Biomedical Imaging
Cortical Bone Vasculature Imaging via Contrast-enhanced High-resolution Peripheral Quantitative Computed Tomography (HR-pQCT)
2019-2020
Department of Orthopaedic Surgery
Development of M2Hbone - a web-based tool for identification of mouse genes relevant to human bone fragility
2018-2019
Musa Zaid, MD
Department of Orthopaedic Surgery
Patient-Specific Pathologic Femur Fracture Risk Assessment Using Geometrically Precise 3D-Printed Biomechanical Phantoms
2017-2018
Department of Orthopaedic Surgery
3D printing μCT data
2016-2017
Debbie Y. Dang, MD PhD
Department of Orthopaedic Surgery
Collaborator: Alfred C. Kuo, MD PhD
Comparison of fracture healing in Cadherin 11 knockout and wild-type female and male mice
Valentina Pedoia, PhD
Department of Radiology & Biomedical Imaging
Parallel Computing for Deep Learning Image Features Extraction
Department of Medicine
Co-Investigators: Dolores M Shoback, MD;
Dennis Black, PhD
Database Development for Studies of Disease Activity, Metabolic Indices and Inflammation
Anne Schafer, MD
Department of Medicine
Co-PI:John Shepherd, PhD
Co-Investigator: Tiffany Kim, MD
Trabecular Bone Score: Examining Vertebral Bone Quality in Gastric Bypass-Induced Bone Loss and in Other Musculoskeletal Conditions
2015-2016
Department of Orthopaedic Surgery
High-throughput genomic analysis of TGFβ-responsive osteocyte mRNA and miR
Department of Orthopaedic Surgery
Measurement of the effect of cartilage endplate permeability on disc cell function using in situ hybridization
2014-2015
Department of Radiology & Biomedical Imaging
The role of miRNAs in human diabetic bone disease and their association with HRpQCT-derived bone microarchitectural parameter
Shingo Kajimura, PhD
Department of Cell & Tissue Biology
Molecular links between BAT and the musculoskeletal system
Core Voucher Projects
2018-2019
Department of Orofacial Sciences
Age-Related Changes of Macrophage: Implications for Immunomodulation in Periodontal Disease
Caitlin Chambers, MD
Department of Orthopaedic Surgery
Risk Factors For Progressive Degenerative Changes After Meniscal Root Tears as Defined By Longitudinal Magnetic Resonance Imaging
Department of Medicine
Bone density, structure, and estimated strength in transgender youth receiving pubertal suppression in early puberty