Crosstalk in Osteoarthritis: Within and Beyond the Joint
 

Crosstalk in Osteoarthritis: Within and Beyond the Joint (04/16/2021)

 

This half-day symposium will be a virtual meeting to convene researchers from institutions across the US and Europe to recognize osteoarthritis as a disease of the whole joint. Each session is supported by important partners in understanding, preventing, and curing osteoarthritis, including the American Academy of Orthopaedic Surgeons (Session 1), the Arthritis Foundation (Session 2), and the Orthopaedic Research Society (Session 3).   

Join us to discuss the latest discoveries in joint crosstalk in health and disease.

  • Complement the conversation in clinical OA research and stimulate translation
  • Recruit and promote new talent within the field – including groups beyond basic MSK
  • Identify priority research areas and strategies to drive progress

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SPECIAL GUEST SPEAKERS

Lindsey Criswell, MD, MPH, DSc, National Institutes of Health (NIH NIAMS)

Judith Campisi, PhD, The Buck Institute for Research on Aging & Lawrence Berkeley National Laboratory

Kyle Allen, PhD, University of Florida
Frank Beier, PhD, University of Western Ontario
Noël Burtt, PhD, Broad Institute
Kelsey Collins, PhD, Washington University
Kharma Foucher, MD, PhD, University of Illinois at Chicago
Christopher Hernandez, PhD, Cornell University
Nilsson Holguin, PhD, Indiana University
Johnny Huard, PhD, Steadman Philippon Research Institute
Hyeonwoo (Chad) Kim, PhD, Dana-Farber Cancer Institute/
  Harvard Medical School

Ru Liu-Bryan, PhD, University of California at San Diego
Jeffrey Lotz, PhD, University of California at San Francisco
Tristan Maerz, PhD, University of Michigan
Audrey McAlinden, PhD, Washington University
Rachel Miller, PhD, Rush University
Valentina Pedoia, PhD, University of California at San Francisco
Ling Qin, PhD, University of Pennsylvania
Yolande Ramos, PhD, Leiden University Medical Center

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MORE ABOUT THIS EVENT
With the recognition that osteoarthritis is a disease of the whole joint, the organizers led past symposia to discuss the interaction of joint tissues in joint health and disease.  These meetings, including the Joint Crosstalk Symposium in 2016, sponsored by the American Academy of Orthopaedic Surgeons and the Orthopaedic Research Society, and the Symposium on Skeletal Contributions to Joint Degeneration and Osteoarthritis, sponsored by the American Society for Bone and Mineral Research in 2018, raised important questions for future study.  At the 5-year interval since the 2016 meeting, the current symposium revisits these key questions, bringing in new voices and ideas, to chart the course for the future research on crosstalk within and beyond the joint in osteoarthritis.

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EVENT HOSTS
 
CCMBM and UCSF MSK Center logos

UCSF Core Center for Musculoskeletal Biology and Medicine

UCSF Musculoskeletal Center 

OACS and AF logp
OA Clinical Studies Conference
Arthritis Foundation

 


EVENT ORGANIZERS

Tamara Alliston, PhD, University of California at San Francisco
Farshid Guilak, PhD, Shriners Hospitals for Children & Washington University
Jennifer Westendorf, PhD, Mayo Clinic
Thomas Vail, MD, University of California at San Francisco  

EVENT PARTNERS

Center for Skeletal Research

Shriners Hospitals for Children

Washington University

 

Orthopaedic Research Society

 

 

AGENDA (times shown in Pacific Time)
​​​​​​FRIDAY, ​APRIL 16, 2021

                      

8:00-8:30 AM

WELCOME REMARKS & INTRODUCTIONS
Tamara Alliston, PhD, UC San Francisco 
Farshid Guilak, PhD, Shriners Hospitals for Children & Washington University
Jennifer Westendorf, PhD, Mayo Clinic
Thomas Vail, MD, UC San Francisco 

OPENING REMARKS SPEAKER
Lindsey Criswell, MD, MPH, DSc, National Institutes of Health (NIH NIAMS)
Looking to the Future: Osteoarthritis Opportunities for Junior Investigators

 

SESSION 1: CROSSTALK WITHIN THE JOINT​​​
Powered by the American Academy of Orthopaedic Surgeons

SESSION 1 MODERATOR

8:30 AM           Ling Qin, PhD, University of Pennsylvania

SESSION 1 SPEAKERS
​​

8:35 AM


8:43 AM

 


8:51 AM

Audrey McAlinden, PhD, Washington University
Opposing Effects of MicroRNAs on Bone and Cartilage

Tristan Maerz, PhD, University of Michigan
Rspo2-Mediated Wnt/β-Catenin Signaling Orchestrates Pro-inflammatory Crosstalk between Synovial Fibroblasts and Macrophages

Yolande Ramos, PhD, Leiden University Medical Center
Function of Osteoprotegerin: Beyond the Current Paradigm

SESSION 1 PANELISTS

8:59-9:24 AM

Frank Beier, PhD, University of Western Ontario
Noël Burtt, PhD, Broad Institute

 

9:25 AM          BREAK

 

SESSION 2: CROSSTALK BEYOND THE JOINT
Powered by the Arthritis Foundation's OACS Program

SESSION 2 MODERATOR

9:30 AM           Christopher Hernandez, PhD, Cornell University

KEYNOTE SPEAKER

9:35 AM

Judith Campisi, PhD, The Buck Institute for Research on Aging & Lawrence Berkeley National Laboratory
Cellular Senescence, Osteoarthritis and Aging

SESSION 2 SPEAKERS

10:05 AM


10:13 AM

Kelsey Collins, PhD, Washington University
Adipose Tissue is a Critical Regulator of Osteoarthritis

Hyeonwoo (Chad) Kim, PhD, Dana-Farber Cancer Institute/ Harvard Medical School
Irisin Acts on Bone via αV Integrin Receptors

SESSION 2 PANELISTS

10:21-10:45 AM

Nilsson Holguin, PhD, Indiana University
Johnny Huard, PhD, Steadman Philippon Research Institute

 

10:45 AM          BREAK

SESSION 3: CROSSTALK AS A MEDIATOR OF OA PAIN
Powered by Orthopaedic Research Society

SESSION 3 MODERATOR

10:50 AM           Kyle Allen, PhD, University of Florida

SESSION 3 SPEAKERS

10:55 AM



11:03 AM



11:11 AM

​​​​​​Rachel Miller, PhD, Rush University
Crosstalk as a Mediator of OA pain: Focus on Nerves and Cartilage

Valentina Pedoia, PhD, UC San Francisco
Uncovering Associations Between Data-Driven Learned qMRI Biomarkers and Chronic Pain

Kharma Foucher, MD, PhD, University of Illinois at Chicago
Using the Pain-Energy Model to Understand Mobility Limitation in OA

SESSION 3 PANELISTS

11:19-11:44 AM

Ru Liu-Bryan, PhD, UC San Diego
Jeffrey Lotz, PhD, UC San Francisco

 

11:45 AM

CLOSING REMARKS
Tamara Alliston, PhD, UC San Francisco 
Farshid Guilak, PhD, Shriners Hospitals for Children & Washington University
Jennifer Westendorf, PhD, Mayo Clinic
Thomas Vail, MD, UC San Francisco