News

CCMBM 2018 Member Survey Results

Thank you to all the CCMBM membership for taking the time to complete our survey, which was critical to the CCMBM P30 application requesting another 5-years of funding from NIH. We had an overwelming 91% response rate; our average response rate has been 30%. This shows the CCMBM member's motivation and commitment to its goals and enthusiasm to see the Center continue in the future. CCMBM and membership highlights are as follows:

 

CCMBM Membership

Summary of the Grants Supported from the CCMBM Community

CCMBM Activities Members Want Continued 

Interest in CCMBM New Services/Tools


Congratulations to the 2018 CCMBM grantees

PILOT/FEASIBILITY (FUNDER)

Doug Gould, PhD, Professor, Department of Ophthalmology, Mechanistic and Therapeutic Examination of Congenital Skeletal Defects in Col4a1 Mutant Mice (CCMBM and REAC)
 
Stephen Rosenthal, MD, Department of Medicine, Bone Density, Structure, and Estimated Strength in Transgender Youth Receiving Pubertal Suppression in Early Puberty (CTSI)
 
Liping Wang, MD, PhD, Assistant Professional Researcher, Department of Medicine, Role of Estrogen Receptor Alpha Signaling in Hypothalamus on Bone Metabolism during Lactation and Post Weaning Recovery (NCOEWH)
 
Rosanna Wustrack, MD, Assistant Professor, Department of Orthopaedic Surgery, Identifying and enhancing the host immune response in adult soft tissue sarcoma (CTSI)

TOOLS & TECHNOLOGY

Alan Dang, MD, Assistant Professor, Department of Orthopaedic Surgery, 3D printing μCT data

Musa Zaid, MD, Resident Physician, Department of Orthopaedic Surgery, Patient-Specific Pathologic Femur Fracture Risk Assessment using Geometrically Precise 3D-Printed Biomechanical Phantoms


CORE VOUCHER PROGRAM

Caitlin Chambers, MD, Sports Medicine Fellow, Department of Orthopaedic Surgery, Risk Factors For Progressive Degenerative Changes After Meniscal Root Tears As Defined By Longitudinal Magnetic Resonance Imaging

Daniel Clark, DDS, PhD, Postdoctoral Scholar, Department of Orofacial Sciences, Age-Related Changes of Macrophage: Implications for Immunomodulation in Periodontal Disease          

Janet Lee, MD, MPH, Clinical Fellow, Department of Medicine, Bone density, structure, and estimated strength in transgender youth receiving pubertal suppression in early puberty     


Beyond Boundaries: Translating Discoveries to Promote an Active and Healthy Lifestyle

The NIH P30 Core Center for Musculoskeletal Biology and Medicine (CCMBM) hosted a special two-day scientific retreat last month along with the Department of Orthopaedic Surgery at UCSF's Mission Bay campus during September 12-13, 2017. Special guest Scott Parazynski, MD, spoke about pushing limits in science and medicine as an astronaut, physician, pilot, inventor, and co-investigator on NASA/UCSF collaborative projects. In addition, the first day featured interactive exhibits, slam-style talks & posters by trainees, and a reception. The second day of the retreat featured keynote lectures by Judith Campisi, PhDHolly Ingraham, PhD; and David Sassoon, PhD, along with concurrent sessions, and a poster session. Nearly 170 participants attended, including CCMBM members, and other UC San Francisco, UC Berkeley, and Stanford University musculoskeletal researchers, clinicians, and trainees.

L-R: Jeffrey Lotz, PhD, CCMBM Director; Tamara Alliston, PhD, Scientific Retreat Chair; Scott Parazynski, MD, keynote speaker. Photo by Tue Nam Ton.

​In each session, scientists discussed their efforts to tackle musculoskeletal problems, from osteoporosis to rotator cuff injury.  Whether addressing these questions from a basic, translational, or clinical perspective, the CCMBM provided Core resources and pilot grant funding to support this work.  In this way, the CCMBM aims to strengthen the resources and community of new and established investigators to improve musculoskeletal health.

Congratulations to the Slam Talk and Poster winners!
Sarah Wong gives slam talk to event attendees. Photo by Tue Nam Ton.
  • Best Slam Talk – Sarah Wong. Slam Talk Title: Where there's a Wnt there's a Way to Mend Broken Bones.
  • Best Postdoc Poster – Katherine Wysham, PhD. Poster Title: Association of High Anti-Cyclic Citrullinated Peptide Seropositivity and Lean Mass Index with Low Bone Mineral Density in Rheumatoid Arthritis.
  • Second Place Postdoc Poster – Annarita Scaramozza, PhD. Poster Title: Identification and characterization of a subset of satellite sells marked by Mx1-Cre.
  • Best Graduate Student Poster – Courtney Mazur. Poster Title: TGF-beta signaling regulates bone quality through osteocyte perilacunar remodeling. 
  • Second Place Grad Student Poster – David Monteiro. Poster Title: A high-throughput hydrogel platform for studying tension-sensitive modulation of TGF-beta signaling.     

The CCMBM would like to thank event sponsors: UCSF Department of Orthopaedic Surgery, Precision Medicine in Rheumatology (PREMIER), the Endocrine Unit at SF-VAMC, and the Center for Disruptive Musculoskeletal Innovations (CDMI). Kudos to Scientific Retreat committee: Tamara Alliston, PhD, Committee Chair; Wenhan Chang, PhD; Lindsey Criswell, MD, MPH; Alexis Dang, MD; Jeffrey Lotz, PhD; Mary Nakamura, MD; Cynthia Neben, PhD; Dolores Shoback, MD; Richard Souza, PhD, PT.